# [SciPy-User] FW: curve fitting by a sum of gaussian with scipy

Charles R Harris charlesr.harris@gmail....
Thu Apr 18 10:41:27 CDT 2013

```On Thu, Apr 18, 2013 at 9:18 AM, Stéphanie haaaaaaaa <
flower_des_iles@hotmail.com> wrote:

> Hi charles,
> Yes, i left out all the distance data points that had zero matches. So, I
> correct this, and i obtain the graph attached.
> I've done an interpolation with the following code using python and scipy :
>
> #!/usr/bin/env python
> # -*- coding:Utf-8 -*-
>
> import numpy as np
> import matplotlib.pyplot as plt
> from matplotlib import pylab
> from scipy import interpolate
> from scipy import stats
>
> data = np.dtype( [ ('distance',np.int), ('effectif',np.int) ] )
> enreg = np.loadtxt('tmp.txt', dtype=data, skiprows=True)
>
> data=zip(enreg['distance'],enreg['effectif'])
>
>
> xmin = -60
> xmax=60
> ymin=0
> ymax=max(enreg['effectif'])+5
>
> ax1=plt.subplot(2,1,1)
> ax1.set_autoscaley_on(False)
> ax1.set_ylim([ymin,ymax])
> ax1.set_xlim([xmin,xmax])
>
> plt.plot(enreg['distance'],enreg['effectif'],color='#347C2C',lw=2)
> plt.fill_between(enreg['distance'],enreg['effectif'],0,color='#4CC417')
>
> #tck= interpolate.splrep(enreg['distance'],enreg['effectif'])
> xnew= np.linspace(enreg['distance'][0],enreg['distance'][-1], 1000)
> #ynew = interpolate.splev(xnew,tck,der=0)
> #plt.plot(xnew, ynew, 'r')
>
> #kernel
> #kde1 = stats.gaussian_kde(enreg['distance'])
> #kdepdf = kde1.evaluate(xnew)
>
>
> #plt.plot(xnew, kdepdf, label='kde', color="r")
>
> tck= interpolate.splrep(enreg['distance'],enreg['effectif'])
> xnew= np.linspace(enreg['distance'][0],enreg['distance'][-1], 1000)
> ynew = interpolate.splev(xnew,tck,der=0)
> plt.plot(xnew, ynew, 'r')
>
>
> plt.subplot(2,1,2)
> ax2 = plt.subplot(212, sharex=ax1)
>
> for dist, eff in data: # distance dans mon histogramme + effectif dans
> chaque classe
>     for e in np.arange(eff): # np.arrange(3) = array([0, 1, 2])
>         #print "%d,%d : %d" %(dist,eff,e)
>         emod=e+1
>         ax2.scatter(dist,-emod,marker='s',color='#B048B5') # pour qu'il
> n'y ait pas d'overlappe
>
> #plt.xlim(0,100)
>
> ax1.xaxis.tick_top()
> # Set the X Axis label.
> ax1.set_xlabel('Position from significant crosslink site',fontsize=12)
> ax1.xaxis.set_label_position('top')
> ax1.axvline(0, color='black', lw=2)
> # Set the Y Axis label.
> ax1.set_ylabel('# of piRNAs',fontsize=12)
>
>
> ax2.axes.get_xaxis().set_visible(False)
> ax2.axes.get_yaxis().set_visible(False)
> ax2.axvline(0, color='black', lw=2)
>
>
>
>
> plt.setp( ax2.get_xticklabels(), visible=False)
> plt.setp( ax2.get_yticklabels(), visible=False)
> plt.show()
>
> What do you think about it ?
>
>
Certainly looks better ;) Not my field so I can't say more.

For gaussian kernel density estimation there is
scipy.stats.gaussian_kdethat might be worth fooling with, although the
notes imply that multimodal
distributions tend to be over smoothed.

<snip>

Chuck

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